Targeted metagenomics: a high-resolution metagenomics approach for specific gene clusters in complex microbial communities
نویسندگان
چکیده
منابع مشابه
Metagenomics and Microbial Communities
Metagenomics is the genomic analysis of microbial communities. This new science provides access to organisms that are recalcitrant to culturing, as are the vastmajority of microorganismsonEarth.Metagenomics therebyoffers a first peek at thewide varietyof life that has never been studied, thus providing new insight into the structure and function of ecosystems as diverse as the oceans and the hu...
متن کاملComparative metagenomics of microbial communities.
The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content a...
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Metagenomics is the study of genomes directly sequenced from an environment. The goal of metagenomics is to understand the ecosystems by identifying the community members and the genes in the environment, and microbial organisms are a main target of the research [2] [3]. Microbial metagenomics enables to access uncultured microbial organisms, thus obtained sequences are composed of various spec...
متن کاملMetagenomics: genomic analysis of microbial communities.
Uncultured microorganisms comprise the majority of the planet's biological diversity. Microorganisms represent two of the three domains of life and contain vast diversity that is the product of an estimated 3.8 billion years of evolution. In many environments, as many as 99% of the microorganisms cannot be cultured by standard techniques, and the uncultured fraction includes diverse organisms t...
متن کاملMetagenomics for mining new genetic resources of microbial communities.
Recent progress has revealed that the capture of genetic resources of complex microbial communities in metagenome libraries allows the discovery of a richness of new enzymatic diversity that had not previously been imagined. Activity-based screening of such libraries has demonstrated that this new diversity is not simply variations on known sequence themes, but rather the existence of entirely ...
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ژورنال
عنوان ژورنال: Environmental Microbiology
سال: 2011
ISSN: 1462-2912
DOI: 10.1111/j.1462-2920.2011.02438.x